In many administrative entities, there is little information on the accessibility of critical resources such as food, water, healthcare and fuel.Yet the lack of accessibility to critical resources can be a risk-mitigating factor.Indeed, people Sunflower Seeds who are not physically threatened by a hazard can be put at risk by the fact that they lac
A Phase 2a Randomized, Double-Blind, Dose-Optimizing Study to Evaluate the Immunogenicity and Safety of a Bivalent DNA Vaccine for Hemorrhagic Fever with Renal Syndrome Delivered by Intramuscular Electroporation
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic hantaviruses found in Asia and Europe, respectively.DNA vaccines targeting the envelope glycoproteins of these viruses have been constructed and found to elicit neutralizing antibodies when delivered to humans by various technologies including intramuscular electroporation.Here, we report
The contribution of signalling devices to comprehension in english as foreign language.
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Identification of cellular microRNA miR-188-3p with broad-spectrum anti-influenza A virus activity
Abstract Background Influenza A virus (IAV) continues to pose serious Cutouts threats to public health.The current prophylaxis and therapeutic interventions for IAV requires frequent changes due to the continuous antigenic drift and antigenic shift of IAV.Emerging evidence indicates that the host microRNAs (miRNAs) play critical roles in intricate
Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery
Introduction: The availability of large-scale biobanks linking genetic data, rich phenotypes, and biological measures is a powerful opportunity for scientific discovery.However, real-world collections frequently have extensive missingness.While missing data prediction is possible, performance is significantly impaired by block-wise missingness inhe