Assessing accessibility to critical resources for volcanic risk management in Goma, Democratic Republic of Congo

In many administrative entities, there is little information on the accessibility of critical resources such as food, water, healthcare and fuel.Yet the lack of accessibility to critical resources can be a risk-mitigating factor.Indeed, people Sunflower Seeds who are not physically threatened by a hazard can be put at risk by the fact that they lac

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A Phase 2a Randomized, Double-Blind, Dose-Optimizing Study to Evaluate the Immunogenicity and Safety of a Bivalent DNA Vaccine for Hemorrhagic Fever with Renal Syndrome Delivered by Intramuscular Electroporation

Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic hantaviruses found in Asia and Europe, respectively.DNA vaccines targeting the envelope glycoproteins of these viruses have been constructed and found to elicit neutralizing antibodies when delivered to humans by various technologies including intramuscular electroporation.Here, we report

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Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery

Introduction: The availability of large-scale biobanks linking genetic data, rich phenotypes, and biological measures is a powerful opportunity for scientific discovery.However, real-world collections frequently have extensive missingness.While missing data prediction is possible, performance is significantly impaired by block-wise missingness inhe

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